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The use of iodine through a seaweed infusion was used to treat thyroid enlargement as early as the 4th century A.D. by Chinese physician Ke-Hung.
This "new substance", found in seaweed ash, was later discovered by Dernard Courtois in 1811. Then in 1813 this substance was tested, and found to be "a new elementary body analogous to chlorine". Later that year it was introduced at a meeting of Imperial Institute of France, and named "iode".
The first medical use was noted in 1816 as a remedy for goitre (goiter), and enlargement of the thyroid.
In 1831 J.B. Boussingault noted that the the inhabitants of the goitrous districts in Columbia "instinctively preferred" the salts that contained the most iodine. It was recommended that cooking salt be iodinized to treat goiter, a common condition at that time.
Years later, in 1895, E.A.G. Baumann discovered that iodine is an invariable constituent of the thyroid.
Iodine as a germicide: 1873, by C.J. Davaine, a french bacteriologist.
Iodine as an anticeptic: 1865, by A.A. Boinet, a french surgeon.
Lugol's solution came about in 1829 by J.G.A. Lugol, a physician in Paris, introducing an aqueous solution, writing three memoirs on the topic.
Iodine as a skin disinfectant: 1908, by german surgeon A. Grossich.
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